Publications in international journals 2014
  • Yachdav G, Kloppmann E, Kajan L, Hecht M, Goldberg T, Hamp T, Hönigschmid P, Schafferhans A, Roos M, Bernhofer M, Richter L, Ashkenazy H, Punta M, Schlessinger A, Bromberg Y, Schneider R, Vriend G, Sander C, Ben-Tal N, Rost AB.
    PredictProtein--an open resource for online prediction of protein structural and functional features.
    Nucleic Acids Res, doi: 10.1093/nar/gku366, 2014 , PDF


  • Nouws J, Wibrand F, van den Brand M, Venselaar H, Duno M, Lund AM, Trautner S, Nijtmans L, Ostergard E.
    A Patient with Complex I Deficiency Caused by a Novel ACAD9 Mutation Not Responding to Riboflavin Treatment.
    JIMD Rep, 12:37-45. doi: 10.1007/8904_2013_242., 2014 , PDF


  • Ferrè S, de Baaij JH, Ferreira P, Germann R, de Klerk JB, Lavrijsen M, van Zeeland F, Venselaar H, Kluijtmans LA, Hoenderop JG, Bindels RJ.
    Mutations in PCBD1 Cause Hypomagnesemia and Renal Magnesium Wasting.
    J Am Soc Nephrol, Mar;25(3):574-86. doi: 10.1681/ASN.2013040337., 2014 , PDF


  • Dijkstra AR, Setyawati MC, Bayjanov JR, Alkema W, van Hijum SA, Bron PA, Hugenholtz J.
    Diversity in robustness of Lactococcus lactis strains during heat stress, oxidative stress, and spray drying stress.
    Appl Environ Microbiol, Jan;80(2):603-11. doi: 10.1128/AEM.03434-13., 2014 , PDF


  • Isberg V, Vroling B, van der Kant R, Li K, Vriend G, Gloriam D.
    GPCRDB: an information system for G protein-coupled receptors.
    Nucleic Acids Res, Jan;42(Database issue):D422-5. doi: 10.1093/nar/gkt1255., 2014 , PDF


  • Loibl M, Klein I, Prattes M, Schmidt C, Kappel L, Zisser G, Gungl A, Krieger E, Pertschy B, Bergler H.
    The Drug Diazaborine Blocks Ribosome Biogenesis by Inhibiting the AAA-ATPase Drg1.
    J Biol Chem, Feb 14;289(7):3913-22. doi: 10.1074/jbc.M113.536110., 2014 , PDF


  • Liu M, Bienfait B, Sacher O, Gasteiger J, Siezen RJ, Nauta A, Geurts JM.
    Combining chemoinformatics with bioinformatics: in silico prediction of bacterial flavor-forming pathways by a chemical systems biology approach "reverse pathway engineering".
    PLoS One, Jan 8;9(1):e84769. doi: 10.1371/journal.pone.0084769., 2014 , PDF


  • Handtke S, Schroeter R, Jürgen B, Methling K, Schlüter R, Albrecht D, van Hijum SA, Bongaerts J, Maurer KH, Lalk M, Schweder T, Hecker M, Voigt B.
    Bacillus pumilus reveals a remarkably high resistance to hydrogen peroxide provoked oxidative stress.
    PLoS One, Jan 20;9(1):e85625. doi: 10.1371/journal.pone.0085625., 2014 , PDF


  • Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte K, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E.
    Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
    Proc Natl Acad Sci U S A, Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111., 2014 , PDF


  • Ballouz S, Liu JY, Oti M, Gaeta B, Fatkin D, Bahlo M, Wouters MA.
    Candidate disease gene prediction using Gentrepid: application to a genome-wide association study on coronary artery disease.
    Mol Genet Genomic Med, Jan;2(1):44-57. doi: 10.1002/mgg3.40., 2014 , PDF


  • Synofzik M, Müller Vom Hagen J, Haack TB, Wilhelm C, Lindig T, Beck-Wödl S, Nabuurs SB, van Kuilenburg AB, de Brouwer AP, Schöls L.
    X-linked Charcot-Marie-Tooth disease, Arts syndrome, and prelingual non-syndromic deafness form a disease continuum: evidence from a family with a novel PRPS1 mutation.
    Orphanet J Rare Dis, Feb 14;9(1):24. doi: 10.1186/1750-1172-9-24., 2014 , PDF


  • Verhagen LM, de Jonge MI, Burghout P, Schraa K, Spagnuolo L, Mennens S, Eleveld MJ, van der Gaast-de Jongh CE, Zomer A, Hermans PW, Bootsma HJ.
    Genome-Wide Identification of Genes Essential for the Survival of Streptococcus pneumoniae in Human Saliva.
    PLoS One, Feb 25;9(2):e89541. doi: 10.1371/journal.pone.0089541., 2014 , PDF


  • de Gouw D, Hermans PW, Bootsma HJ, Zomer A, Heuvelman K, Diavatopoulos DA, Mooi FR.
    Differentially expressed genes in Bordetella pertussis strains belonging to a lineage which recently spread globally.
    PLoS One, Jan 8;9(1):e84523. doi: 10.1371/journal.pone.0084523. Erratum in: PLoS One. 2014;9(1). doi: 10.1371/annotation/1b2cfe52-aaea-4148-aa72-a74c78550192., 2014 , PDF


  • Kopit LM, Kim EB, Siezen RJ, Harris LJ, Marco ML.
    Safety of the Surrogate Microorganism Enterococcus faecium NRRL B-2354 for Use in Thermal Process Validation.
    Appl Environ Microbiol, Mar;80(6):1899-909. doi: 10.1128/AEM.03859-13., 2014 , PDF


  • van der Linden L, Ulferts R, Nabuurs SB, Kusov Y, Liu H, George S, Lacroix C, Goris N, Lefebvre D, Lanke KH, De Clercq K, Hilgenfeld R, Neyts J, van Kuppeveld FJ.
    Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.
    Antiviral Res, Mar;103:17-24. doi: 10.1016/j.antiviral.2013.12.012., 2014 , PDF


  • Ferrando ML, van Baarlen P, Orrù G, Piga R, Bongers RS, Wels M, De Greeff A, Smith HE, Wells JM.
    Carbohydrate Availability Regulates Virulence Gene Expression in Streptococcus suis.
    PLoS One, Mar 18;9(3):e89334. doi: 10.1371/journal.pone.0089334., 2014 , PDF


  • Bottacini F, O'Connell Motherway M, Kuczynski J, O'Connell KJ, Serafini F, Duranti S, Milani C, Turroni F, Lugli GA, Zomer A, Zhurina D, Riedel C, Ventura M, van Sinderen D.
    Comparative genomics of the Bifidobacterium breve taxon.
    BMC Genomics, Mar 1;15:170. doi: 10.1186/1471-2164-15-170., 2014 , PDF


  • Brazas MD, Lewitter F, Schneider MV, van Gelder CW, Palagi PM.
    A Quick Guide to Genomics and Bioinformatics Training for Clinical and Public Audiences.
    PLoS Comput Biol, Apr 10;10(4):e1003510. doi: 10.1371/journal.pcbi.1003510., 2014 , PDF


  • Cnossen WR, Te Morsche RH, Hoischen A, Gilissen C, Chrispijn M, Venselaar H, Mehdi S, Bergmann C, Veltman JA, Drenth JP.
    Whole-exome sequencing reveals LRP5 mutations and canonical Wnt signaling associated with hepatic cystogenesis.
    Proc Natl Acad Sci U S A, Apr 8;111(14):5343-8. doi: 10.1073/pnas.1309438111., 2014 , PDF


  • Moon-van der Staay SY, van der Staay GW, Michalowski T, Jouany JP, Pristas P, Javorský P, Kišidayová S, Varadyova Z, McEwan NR, Newbold CJ, van Alen T, de Graaf R, Schmid M, Huynen MA, Hackstein JH.
    The symbiotic intestinal ciliates and the evolution of their hosts.
    Eur J Protistol, Apr;50(2):166-73. doi: 10.1016/j.ejop.2014.01.004., 2014 , PDF


  • Berntsen KR, Vriend G.
    Anomalies in the refinement of isoleucine.
    Acta Crystallogr D Biol Crystallogr, Apr 1;70(Pt 4):1037-49. doi: 10.1107/S139900471400087X., 2014 , PDF


  • Schuurmans JM, van Hijum SA, Piet JR, Händel N, Smelt J, Brul S, Ter Kuile BH.
    Effect of growth rate and selection pressure on rates of transfer of an antibiotic resistance plasmid between E. coli strains.
    Plasmid, Mar;72:1-8. doi: 10.1016/j.plasmid.2014.01.002., 2014 , PDF


  • Fineran PC, Gerritzen MJ, Suárez-Diez M, Künne T, Boekhorst J, van Hijum SA, Staals RH, Brouns SJ.
    Degenerate target sites mediate rapid primed CRISPR adaptation.
    Proc Natl Acad Sci U S A, Apr 22;111(16):E1629-38. doi: 10.1073/pnas.1400071111., 2014 , PDF


  • Ritschel T, Hermans SM, Schreurs M, van den Heuvel JJ, Koenderink JB, Greupink R, Russel FG.
    In Silico Identification and in Vitro Validation of Potential Cholestatic Compounds through 3D Ligand-Based Pharmacophore Modeling of BSEP Inhibitors.
    Chem Res Toxicol, May 19;27(5):873-81. doi: 10.1021/tx5000393., 2014 , PDF


  • Ritschel T, Schirris TJ, Russel FG.
    KRIPO - a structure-based pharmacophores approach explains polypharmacological effects.
    J Cheminform, Mar 11;6(Suppl 1):O26. eCollection 2014 Mar., 2014 , PDF


  • Ellero-Simatos S, Fleuren WW, Bauerschmidt S, Dokter WH, Toonen EJ.
    Identification of gene signatures for prednisolone-induced metabolic dysfunction in collagen-induced arthritic mice.
    Pharmacogenomics, Apr;15(5):629-41. doi: 10.2217/pgs.14.3., 2014 , PDF


  • van der Kant R, Vriend G.
    Alpha-bulges in g protein-coupled receptors.
    Int J Mol Sci, May 6;15(5):7841-64. doi: 10.3390/ijms15057841., 2014 , PDF


  • Szklarczyk R, Nooteboom M, Osiewacz HD.
    Control of mitochondrial integrity in ageing and disease.
    Philos Trans R Soc Lond B Biol Sci, Jul 5;369(1646). pii: 20130439. Review., 2014 , PDF


  • Speijer D, Manjeri GR, Szklarczyk R.
    How to deal with oxygen radicals stemming from mitochondrial fatty acid oxidation.
    Philos Trans R Soc Lond B Biol Sci, Jul 5;369(1646). pii: 20130446. Review., 2014 , PDF


  • Notebaart RA, Szappanos B, Kintses B, Pál F, Györkei A, Bogos B, Lázár V, Spohn R, Csörg? B, Wagner A, Ruppin E, Pál C, Papp B.
    Network-level architecture and the evolutionary potential of underground metabolism.
    Proc Natl Acad Sci USA, 2014 Aug 12;111(32):11762-7. doi: 10.1073/pnas.1406102111. Epub 2014 Jul 28., 2014 , PDF


  • Manuel Corpas, Rafael C. Jimenez, Erik Bongcam-Rudloff, Aidan Budd, Michelle D. Braza, Pedro L. Fernandes, Bruno Gaeta, Celia van Gelder, Eija Korpelainen, Fran Lewitter, Annette McGrath, Daniel MacLean, Patricia M. Palagi, Kristian Rother, Jan Taylor, Allegra Via, Mick Watson, Maria Victoria Schneider and Teresa K. Attwood.
    The GOBLET Training Portal: A Global Repository of Bioinformatics Training Materials, Courses and Trainers
    Bioinformatics (2014), doi: 10.1093/bioinformatics/btu601 First published online: September 4, 2014 , PDF


  • Scott J. Lusher, Ross McGuire, Rene C. van Schaik, C. David Nicholson, Jacob de Vlieg
    Data-driven medicinal chemistry in the era of big data
    Drug Discovery Today, Volume 19, Issue 7, July 2014, Pages 859–868, 2014 , PDF


  • Andreadaki M, Morgan RN, Deligianni E, Kooij TW, Santos JM, Spanos L, Matuschewski K, Louis C, Mair GR, Siden-Kiamos I.
    Genetic crosses and complementation reveal essential functions for the Plasmodium stage-specific actin2 in sporogonic development.
    Cell Microbiol., May;16(5):751-67. doi: 10.1111/cmi.12274., 2014 , PDF


  • Bronkhorst AW, van Cleef KW, Venselaar H, van Rij RP.
    A dsRNA-binding protein of a complex invertebrate DNA virus suppresses the Drosophila RNAi response.
    Nucleic Acids Res., Oct 29;42(19):12237-48. doi: 10.1093/nar/gku910., 2014 , PDF


  • Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EM, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A.
    MPV17L2 is required for ribosome assembly in mitochondria.
    Nucleic Acids Res., Jul;42(13):8500-15. doi: 10.1093/nar/gku513, 2014 , PDF


  • Du Y, Cai KF, Chen S, Cizek P, Lin T.
    Facile preparation and thermoelectric properties of BI2 Te3 based alloy nanosheet/PEDOT:PSS composite films.
    ACS Appl Mater Interfaces., Apr 23;6(8):5735-43. doi: 10.1021/am5002772., 2014


  • Dutilh BE, Cassman N, McNair K, Sanchez SE, Silva GG, Boling L, Barr JJ, Speth DR, Sequritan V, Aziz RK, Felts B, Dinsdale EA, Mokili JL, Edwards RA.
    A highly abundant bacteriophage discovered in the unknown sequences of human faecal metagenomes.
    Nat Commun, Jul 24;5:4498. doi: 10.1038/ncomms5498., 2014 , PDF


  • Dutilh BE, Thompson CC, Vicente AC, Marin MA, Lee C, Silva GG, Schmieder R, Andrade BG, Chimetto L, Cuevas D, Garza DR, Okeke IN, Aboderin AO, Spangler J, Ross T, Dinsdale EA, Thompson FL, Harkins TT, Edwards RA.
    Comparative genomics of 274 Vibrio cholerae genomes reveals mobile functions structuring three niche dimensions.
    BMC Genomics, Aug 5;15:654. doi: 10.1186/1471-2164-15-654., 2014 , PDF


  • ElRakaiby M, Dutilh BE, Rizkallah MR, Boleij A, Cole JN, Aziz RK.
    Pharmacomicrobiomics: the impact of human microbiome variations on systems pharmacology and personalized therapeutics.
    OMICS, Jul;18(7):402-14. doi: 10.1089/omi.2014.0018., 2014 , PDF


  • Ghamrawi S, Renier G, Saulnier P, Cuenot S, Zykwinska A, Dutilh BE, Thornton C, Faure S, Bouchara JP.
    Cell wall modifications during conidial maturation of the human pathogenic fungus Pseudallescheria boydii.
    PLoS One., Jun 20;9(6):e100290. doi: 10.1371/journal.pone.0100290., 2014 , PDF


  • de Gouw D, de Jonge MI, Hermans PW, Wessels HJ, Zomer A, Berends A, Pratt C, Berbers GA, Mooi FR, Diavatopoulos DA.
    Proteomics-identified Bvg-activated autotransporters protect against Bordetella pertussis in a mouse model.
    PLoS One, Aug 18;9(8):e105011. doi: 10.1371/journal.pone.0105011., 2014 , PDF


  • Haussig JM, Burgold J, Hafalla JC, Matuschewski K, Kooij TW.
    Signatures of malaria vaccine efficacy in ageing murine immune memory.
    Parasite Immunol., May;36(5):199-206. doi: 10.1111/pim.12104., 2014 , PDF


  • Haussig JM, Matuschewski K, Kooij TW.
    Identification of vital and dispensable sulfur utilization factors in the Plasmodium apicoplast.
    PLos One., Feb 21;9(2):e89718. doi: 10.1371/journal.pone.0089718., 2014 , PDF


  • Kenthirapalan S, Waters AP, Matuschewski K, Kooij TW.
    Copper-transporting ATPase is important for malaria parasite fertility.
    Mol Microbiol., Jan;91(2):315-25. doi: 10.1111/mmi.12461. , 2014 , PDF


  • Krieger E, Vriend G.
    YASARA View - molecular graphics for all devices - from smartphones to workstations.
    Bioinformatics, Oct 15;30(20):2981-2. doi: 10.1093/bioinformatics/btu426. , 2014 , PDF


  • Kwon TJ, Oh SK, Park HJ, Sato O, Venselaar H, Choi SY, Kim S, Lee KY, Bok J, Lee SH, Vriend G, Ikebe M, Kim UK, Choi JY.
    The effect of novel mutations on the structure and enzymatic activity of unconventional myosins associated with autosomal dominant non-syndromic hearing loss.
    Open Biol., Jul;4(7). pii: 140107. doi: 10.1098/rsob.140107., 2014 , PDF


  • Lim YW, Cuevas DA, Silva GG, Aquinaldo K, Dinsdale EA, Haas AF, Hatay M, Sanchez SE, Wegley-Kelly L, Dutilh BE, Harkins TT, Lee CC, Tom W, Sandin SA, Smith JE, Zgliczynski B, Vermeij MJ, Rohwer F, Edwards RA.
    Sequencing at sea: challenges and experiences in Ion Torrent PGM sequencing during the 2013 Southern Line Islands Research Expedition.
    PeerJ., Aug 19;2:e520. doi: 10.7717/peerj.520. , 2014 , PDF


  • Lounnas V, Wedler HB, Newman T, Schaftenaar G, Harrison JG, Nepomunceno G, Pemberton R, Tantillo DJ, Vriend G.
    Visually impaired researchers get their hands on quantum chemistry: application to a computational study on the isomerization of a sterol.
    J Comput Aided Mol Des., Nov;28(11):1057-67. doi: 10.1007/s10822-014-9782-7., 2014 , PDF


  • Madrigal I, Alvarez-Mora MI, Karlberg O, Rodriguez-Revenga L, Elurbe DM, Rabionet R, Mur A, Pie J, Ballesta F, Sauer S, Syvanen AC, Mila M.
    Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes.
    J Clin Pathol, Dec;67(12):1099-103. doi: 10.1136/jclinpath-2014-202537., 2014 , PDF


  • Malik S, Siezen RJ, Renckens B, Vaneechoutte M, Vanderleyden J, Lebeer S.
    Draft Genome Sequence of Lactobacillus plantarum CMPG5300, a Human Vaginal Isolate.
    Genome Announc., Nov 13;2(6). pii: e01149-14. doi: 10.1128/genomeA.01149-14., 2014 , PDF


  • Mobegi FM, van Hijum SA, Burghout P, Bootsma HJ, de Vries SP, van der Gaast-de Jongh CE, Simonetti E, Langereis JD, Hermans PW, de Jonge MI, Zomer A.
    From microbial gene essentiality to novel antimicrobial drug targets.
    BMC Genomics, Nov 5;15:958. doi: 10.1186/1471-2164-15-958., 2014 , PDF


  • O'Connell KJ, Motherway MO, Liedtke A, Fitzgerald GF, Paul Ross R, Stanton C, Zomer A, van Sinderen D.
    Transcription of two adjacent carbohydrate utilization gene clusters in Bifidobacterium breve UCC2003 is controlled by LacI- and repressor open reading frame kinase (ROK)-type regulators.
    Appl Environ Microbiol., Jun;80(12):3604-14., 2014 , PDF


  • Rosentul DC, Delsing CE, Jaeger M, Plantinga TS, Oosting M, Costantini I, Venselaar H, Joosten LA, van der Meer JW, Dupont B, Kullberg BJ, Sobel JD, Netea MG.
    Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis.
    Front Microbiol., Sep 23;5:483. doi: 10.3389/fmicb.2014.00483., 2014 , PDF


  • Silva GG, Cuevas DA, Dutilh BE, Edwards RA.
    FOCUS: an alignment-free model to identify organisms in metagenomes using non-negative least squares.
    PeerJ, Jun 5;2:e425. doi: 10.7717/peerj.425. , 2014 , PDF


  • Steenenga WT, Mischke M, Lute C, Boekschoten MV, Pruis MG, Lendvai A, Verkade HJ, Boekhorst J, Timmerman HM, Plosch T, Muller M.
    Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice.
    Biol Sex Differ., Aug 29;5:11. doi: 10.1186/s13293-014-0011-9., 2014 , PDF


  • Szalowska E, Tesfay HA, van Hijum SA, Kersten S.
    Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology.
    BMC Genomics, Dec 15;15:1106. doi: 10.1186/1471-2164-15-1106., 2014 , PDF


  • Touw WG, Vriend G.
    BDB: databank of PDB files with consistent B-factors.
    Protein Eng Des Sel., Nov;27(11):457-62. doi: 10.1093/protein/gzu044., 2014 , PDF


  • van der Lee R, Buljan M, Lang B, Weatheritt RJ, Daughdrill GW, Dunker AK, Fuxreiter M, Gough J, Gsponer J, Jones DT, Kim PM, Kriwacki RW, Oldfield CJ, Pappu RV, Tompa P, Uversky VN, Wright PE, Babu MM.
    Classification of intrinsically disordered regions and proteins.
    Chem Rev., Jul 9;114(13):6589-631. doi: 10.1021/cr400525m., 2014 , PDF


  • van der Lee R, Lang B, Kruse K, Gsponer J, Sanchez de Groot N, Huynen MA, Matouschek A, Fuxreiter M, Babu MM.
    Intrinsically disordered segments affect protein half-life in the cell and during evolution.
    Cell Rep., Sep 25;8(6):1832-44. doi: 10.1016/j.celrep.2014.07.055., 2014 , PDF


  • van der Meer LT, Waanders E, Levers M, Venselaar H, Roeleveld D, Lanvers C, Bruggemann RJ, Kuiper RP, Hoogerbrugge PM, van Leeuwen FN, te Loo DM.
    A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics.
    Blood, Nov 6;124(19):3027-9. doi: 10.1182/blood-2014-06-582627., 2014 , PDF


  • Wammes AE, Hendriks TG, Amatdjais-Groenen HI, Wijdeven MA, van Hest JC, van Delft FL, Ritschel T, Rutjes FP.
    Influence of azide incorporation on binding affinity by small papain inhibitors.
    Bioorg Med Chem., Oct 15;22(20):5593-603. doi: 10.1016/j.bmc.2014.06.001. , 2014 , PDF


  • Wanschers BF, Szklarczyk R, van den Brand MA, Jonckheere A, Suijskens J, Smeets R, Rodenburg RJ, Stephan K, Helland IB, Elkamil A, Rootwelt T, Ott M, van den Heuvel L, Nijtmans LG, Huynen MA.
    A mutation in the human CBP4 ortholog UQCC3 impairs complex III assembly, activity and cytochrome b stability.
    Hum Mol Genet., Dec 1;23(23):6356-65. doi: 10.1093/hmg/ddu357. , 2014 , PDF


  • Wilson CM, Loach D, Lawley B, Bell T, Sims IM, O'Toole PW, Zomer A, Tannock GW.
    Lactobacillus reuteri 100-23 modulates urea hydrolysis in the murine stomach.
    Appl Environ Microbiol., Oct;80(19):6104-13. doi: 10.1128/AEM.01876-14. , 2014 , PDF


  • Kenthirapalan S, Waters AP, Matuschewski K, Kooij TWA.
    Copper-transporting ATPase is important for malaria parasite fertility
    Molecular Microbiology, 91(2) 315-25. doi: 10.1111/mmi.12461 , 2014 , PDF


  • Lagemaat LN, Van de Nijhof B, Bosch DGM, Kohansal-Nodehi M, Keerthikumar S, Heimel JA.
    Age-related decreased inhibitory vs. excitatory gene expression in the adult autistic brain
    Frontiers in Neuroscience, 8, 1-9. doi: 10.3389/fnins.2014.00394, 2014


  • Short KR, Vissers M, de Kleijn S, Zomer AL, Kedzierska K, Grant E, Reading PC, Hermans PWM, Ferwerda G, Diavatopoulos DA
    Bacterial lypopolysaccharide inhibits influenza virus infiection of human macrophages and the consequent induction of CD8+ T cell immunity
    Journal of Innate Immunity, 6(2), 129-39. doi: 10.1159/000353905, 2014 , PDF


  • Dijkstra AR, Alkema W, Starrenburg MJ, Hugenholtz J, van Hijum SA, Bron PA.
    Fermentation-induced variation in heat and oxidative stress phenotypes of Lactococcus lactis MG1363 reveals transcriptome signatures for robustness.
    Microb Cell Fact., Nov 4;13:148. doi: 10.1186/s12934-014-0148-6., 2014 , PDF


  • Zeeuwen PL, Ederveen TH, van der Krieken DA, Niehues H, Boekhorst J, Kezic S, Hanssen DA, Otero ME, van Vlijmen-Willems IM, Rodijk-Olthuis D, Falcone D, van den Bogaard EH, Kamsteeg M, de Koning HD, Zeeuwen-Franssen ME, van Steensel MA, Kleerebezem M, Timmerman HM, van Hijum SA, Schalkwijk J
    Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin
    J Allergy Clin Immunol, 2017 Apr;139(4):1368-71, 2014 , PDF